By Claus Cursiefen, Albert S. Jun
This booklet presents state-of-the-art details on sleek minimally invasive lamellar transplant suggestions for Fuchs endothelial dystrophy (FED), reminiscent of Descemet stripping computerized endothelial keratoplasty (DSAEK) and Descemet membrane endothelial keratoplasty (DMEK). as well as transparent step by step descriptions of approaches, counsel is on the market on donor tissue education, capability intra- and postoperative issues, and worry administration. destiny treatment plans within the kind of scientific, cell-based methods also are mentioned. to accomplish the image, correct details is incorporated at the pathophysiology, medical beneficial properties, and differential analysis of FED. This ebook may be of curiosity to all who desire to find out about the dramatic advancements in corneal transplantation and clinical remedy which are remodeling the administration of FED.
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Additional resources for Current Treatment Options for Fuchs Endothelial Dystrophy
If the tear film is made hypertonic, it will extract water from the cornea according to the phenomenon called osmosis. Clinical experience shows that in particular epithelial edema can be influenced . To decrease the stromal edema, the human cornea would need contact with a fluid of such hypertonicity that treatment would become very painful and damaging . Sodium chloride eye drops penetrate the epithelium poorly and can therefore attract only the water from the epithelial bullae . For more than 40 years, a 5 % sodium chloride solution is in use .
2006;113:2187–97. 66. Gattey D, Zhu AY, Stagner A, Terry MA, Jun AS. Fuchs endothelial corneal dystrophy in patients with myotonic dystrophy: a case series. Cornea. 2014;33(1):96–8. 67. Du J, Aleff RA, Soragni E, Kalari K, Nie J, Tang X, Davila J, Kocher JP, Patel SV, Gottesfeld JM, Baratz KH, Wieben ED. RNA toxicity and missplicing in the common eye 5 disease Fuchs Endothelial Corneal Dystrophy. J Biol Chem. 2015;290(10):5979–90. 68. Payrau P, Dohlman CH. Medical treatment of corneal edema. Int Ophthalmol Clin.
Clinical study of Fuchs corneal endothelial dystrophy leading to penetrating keratoplasty. Arch Ophthalmol. 2006;124:777–80. 44. Eghrari AO, Daoud Y, Gottsch JD. Cataract surgery in Fuchs corneal dystrophy. Curr Opin Ophthalmol. 2010;21:15–9. 45. Krachmer JH. Posterior polymorphous corneal dystrophy: a disease characterized by epitheliallike endothelial cells which influence management and prognosis. Trans Am Ophthalmol Soc. 1985;83:413–75. 46. Aldave AJ, Ann LB, Frausto RF, Nguyen CK, Yu F, Raber IM.