Congenital Cataract: A Concise Guide to Diagnosis and by Ian Christopher Lloyd, Scott R. Lambert

By Ian Christopher Lloyd, Scott R. Lambert

This e-book goals to help ophthalmologists in offering the very best deal with kids with congenital cataracts. the whole sufferer pathway is roofed, from preoperative evaluation via software of a few of the surgical concepts to postoperative care and administration of issues. one of the subject matters mentioned are new advancements in molecular genetics suitable to sufferer evaluate, intraocular lens strength formulation, and the findings of the newborn Aphakia remedy research. The surgical part describes anterior capsulotomy, lensectomy, choice of intraocular lens (IOL) strength, IOL implantation within the capsular bag, posterior capsulotomy strategies, using secondary IOLs and iris-fixated IOLs in childrens, and surgical administration in constructing international locations. visible results after surgical procedure also are absolutely addressed, with chapters at the incidence of strabismus, nystagmus, and bad stereopsis.

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Additional info for Congenital Cataract: A Concise Guide to Diagnosis and Management

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Assessment by a geneticist may follow initial ophthalmological examination, where a detailed family history will also be taken, along with information regarding antenatal, perinatal and postnatal health [71]. Given the extensive number of possible disorders underlying the development of congenital or childhood cataract [49], the route to precise diagnosis of the underlying genetic cause can be complex with input required from multiple medical specialities in addition to ophthalmology and genetics, including dysmorphology, neurology, metabolics, and orthopaedics [64].

Epidemiology of cataract in childhood: a global perspective. J Cataract Refract Surg. 1997;23 Suppl 1:601–4. 11. Gilbert C, Foster A. Childhood blindness in the context of VISION 2020: the right to sight. Bull World Health Organ. 2001;79:227–32. 12. Gilbert CE, Anderton L, Dandona L, Foster A. Prevalence of visual impairment in children: a review of available data. Ophthalmic Epidemiol. 1999;6(1):73–82. 13. Gillespie RL, O’Sullivan J, Ashworth J, Bhaskar S, Williams S, Biswas S, Kehdi E, Ramsden SC, ClaytonSmith J, Black GC, Lloyd IC.

L. M. Black 32 Fig. 1 Schematic diagram of the lens Sutures Anterior epithelium Capsule OFZ Primary fibres of the lens mass, and the removal of metabolic waste products [21]. Water is circulated through membrane channels comprised of aquaporin 1 (AQP1) in lens epithelial cells [22], and major intrinsic protein (MIP) in fibre cells [23]. The breakdown of glucose by anaerobic metabolism is the main source of energy for both growth and homeostasis in the lens. Uptake of glucose from the aqueous humour appears to be mediated by the glucose transporter, GLUT1 in the lens epithelium, for circulation throughout the structure.

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