Antigen-presenting cells and the eye by Manfred Zierhut, Hans-Georg Rammensee, Wayne Streilein

By Manfred Zierhut, Hans-Georg Rammensee, Wayne Streilein

In recent times the significance of antigen-presenting cells and their impression at the eyes has been elucidated. we have now realized that almost each constitution of the attention harbors those cells, but they fluctuate of their actions and hence within the ways that they guard opposed to - or perform - illnesses of the attention. Antigen-Presenting Cells and the attention summarizes present wisdom approximately ACPs commonly, and their position within the eye, specifically.

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Whether macrophages become DCs is a matter of controversy. It is known that APCs in the tissue take up, process, and transport antigens to the secondary lymphoid organs. The state of the APC that sees the antigen is critical to the outcome of the immune response. When antigen is deliberately inoculated with adjuvants that contain “danger” signals, the APCs are apt to induce an inflammatory immune response. The mature APCs travel to the spleen and are deposited in the marginal zone (MZ) of the spleen when they exit the blood through the central arteriole.

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