2014-2015 Basic and Clinical Science Course (BCSC): Section by American Academy of Ophthalmology, Hermann D. Schubert MD

By American Academy of Ophthalmology, Hermann D. Schubert MD

Offers an summary of the constitution and serve as of the retina and its courting to the pigment epithelium, choroid and vitreous. Describes the most important vitreoretinal problems and acceptable diagnostic equipment and therapy principles.

In its final significant revision, part 12 was once re-organized into 3 components. Separate chapters are actually dedicated to age-related macular degeneration, diabetic retinopathy and retinopathy of prematurity, together with the newest imaging innovations and choroidal aspect. chosen healing subject matters comprise laser treatment and vitreoretinal surgery.

Upon of completion of part 12, readers could be capable to:

Select acceptable tools of exam and ancillary stories for the analysis of vitreoretinal disorders
Describe the rules of clinical and surgical operation of vitreoretinal disorders
Incorporate info from significant potential scientific trials within the administration of chosen vitreoretinal issues

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Additional info for 2014-2015 Basic and Clinical Science Course (BCSC): Section 12: Retina and Vitreous

Example text

Berkow TW, Flower RW, Orth DH, Kelley rs. Fluorescein and Indocyanine Green Angiography : Technique and Interpretation. 2nd ed. Ophthalmology Monograph 5. San Francisco: American Academy of Ophthalmology; 1997. Kwiterovich KA, Maguire MG, Murphy RP, et al. Frequency of adverse systemic reactions after fluorescein angiography: results of a prospective study. Ophthalmology. 1991;98(7): 1139-1142. lndocyanine Green Angiography Indocyanine green (ICG) is a water-soluble, tricarbocyanine dye with a molecular weight of775 that is almost completely protein-bound (98%) after intravenous injection.

The retinal and choroidal vessels fill during the transit phase, which lasts 10-15 seconds. Choroidal filling is characterized by a patchy choroidal flush, with choriocapillary lobules often visible. The choroid has a higher flow rate than that of the retinal vessels. The arterial phase of the angiographic study occurs after the choroidal phase, and dye fills the retinal arteries. The arteriovenous phase begins with complete filling of the retinal arteries and capillaries and concludes with laminar filling of the retinal veins.

The venous blood exiting the choroid still has a very high oxygen tension. The RPE cells, which are based on the choriocapillaris, are exposed to the highest oxygen tensions of any perfused tissue, increasing the risk of oxidative damage. The rapid flow in the choroid acts as a heat sink to remove thermal energy from light absorption. Interspersed between the vessels of the choroid are loose connective tissue, fibroblasts, and melanocytes. Sciera The sclera is composed of collagen and a few elastic fibers embedded in a matrix of proteoglycans.

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